Take a drink every time . . .
. . . a new character is named.
. . . a named character dies.
--If it's the significant other of a viewpoint character, drink twice.
--If they come back from the dead, as a wight or otherwise, drink twice.
--If it's a viewpoint character, finish the bottle. (Prologue viewpoint characters don't count. That's just a given.)
. . . a new incestuous couple is mentioned.
. . . there's a sex scene.
--If it involves Dany or Cersei, drink twice.
--If the phrase "she was sopping wet down there" appears, drink twice.
--If it gives you a hint as to one of GRRM's fetishes (like lesbianism or lactation) drink twice.
. . . a nipple is pinched, tweaked or twisted.
--If it actually happens in a sex scene, drink twice.
. . . a course in a feast is lovingly described.
--If the course is lemon cakes, ribs in a crust of garlic and herbs, mashed turnips with butter, cheese and olives, lamprey pie or a Dornish red, drink twice.
. . . one of the following phrases is uttered:
--"Abominations born of incest."
--"It is known."
--"You know nothing, Jon Snow."
--"Winter is coming."
--"I want to see/make him/the bad man fly."
--"The night is dark and full of terrors."
--"Sweet sister"/"Sweet brother."
. . . Arya picks up a new pseudonym.
. . . we're reminded that a long summer means a long winter.
. . . Cersei incorrectly thinks of something as exactly what her father would do.
. . . the direwolves howl. And howl. And howl some more.
. . . ravens deliver information at the speed of Twitter.
. . . you want to punch Bran, Catelyn or Arianne in the face.
Did I miss anything?